Testicles and brain have more in common than you think

Testicles and brain have more in common than you think


At first glance, the testicles and the brain have nothing in common, the first is involved in a function considered trivial, reproductive, while the second is as complex in its structure as in the biological functions it performs, but the Portuguese Researchers working with a British team went beyond these phenomena and revealed a surprising number of similarities between the testes and the human brain in a paper published in Open Biology.

Tissue similarities …

Testicles and brain have more in common than you think

Your first point of comparison is the fabric. Brain cells can be divided into two groups: neurons and glial cells, which in turn comprise four types of cells that support the activity of neurons. The scientists made a similar analogy for testicular cells. The testes that produce sperm, like neurons, are responsible for processing information in the brain. These seminal tubes are made up of germ cells, in which the gametes are born, and Sertoli cells, which make up the tubes. between neurons and sperm. These two organs are also very energy intensive. Both get their energy from lactate, a metabolic product produced by astrocytes in the brain, and Sertoli cells in the testes. This energy is mainly used for cognition and spermatogenesis. and the testicles are also isolated from the rest of the body, this is the immunological privilege given by the blood-brain or blood-testicle barrier.By simplifying its structure, the similarities appear between the testes and the brain. Scientists have looked further and looked at the proteome of the two organs, the amount of proteins they are expressing at any given point in time.

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… and protein

According to the information gathered by scientists, the testes and brain share 13,442 different proteins, more than any other organ studied, 31 in total, which are involved in the function and development of both organs since the testes are part of the neuroendocrine system. Therefore, they communicate closely with the brain, particularly through hormones such as pituitary gonadotropin releasing hormone (GnRH), which is produced by the hypothalamus in the brain. The similarities between these two opposing organs would allow scientists to improve our understanding of the dysfunctions that affect both the testes and the brain. “A connection between the degenerative process of the central nervous system and testicular degeneration has been observed without the presence of pituitary lesions at the same time,” the authors of the article write. Discover Fil de Science! 6:30 p.m., follow the roundup of the week’s scientific news that Futura journalists decipher for you.

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